About this Collection
Growth factors and cytokines are biologically active signaling proteins that regulate cellular communication, proliferation, differentiation, survival, migration, and immune responses. In cell culture, these molecules are routinely added to culture media to control cell fate, maintain specialized cell populations, promote tissue-specific differentiation, and model physiological or pathological signaling pathways.
This collection provides standardized reference guides for commonly used growth factors and cytokines, including their biological functions, signaling pathways, receptor interactions, preparation, storage, recommended working concentrations, and applications in mammalian cell culture, stem cell research, neuroscience, immunology, and regenerative medicine.
Browse Growth Factors & Cytokines
Explore standardized reference guides for growth factors, cytokines, and signaling proteins commonly used to regulate cell proliferation, differentiation, survival, stem cell maintenance, and immune function in mammalian cell culture.
Brain-Derived Neurotrophic Factor (BDNF)
A neurotrophin that promotes neuronal survival, differentiation, synaptic plasticity, and neural development.
Ciliary Neurotrophic Factor (CNTF)
Supports neuronal survival, glial differentiation, and regeneration of the nervous system.
Epidermal Growth Factor (EGF)
Stimulates proliferation, survival, and maintenance of epithelial and stem cells.
Fibroblast Growth Factor 2 (FGF-2)
Supports stem cell self-renewal, angiogenesis, tissue repair, and cellular proliferation.
Flt3 Ligand
Promotes proliferation and differentiation of hematopoietic stem and progenitor cells.
Glial Cell Line-Derived Neurotrophic Factor (GDNF)
Supports the survival and maintenance of dopaminergic and motor neurons.
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Stimulates proliferation and differentiation of granulocyte and macrophage progenitor cells.
Hepatocyte Growth Factor (HGF)
Regulates cell growth, motility, morphogenesis, and tissue regeneration.
Insulin-Like Growth Factor 1 (IGF-1)
Promotes cellular growth, survival, metabolism, and differentiation across diverse cell types.
Interleukin-2 (IL-2)
Supports activation, proliferation, and expansion of T lymphocytes in immune cell cultures.
Interleukin-3 (IL-3)
Promotes proliferation and differentiation of hematopoietic progenitor cells.
Interleukin-6 (IL-6)
Regulates immune responses, inflammation, and survival of multiple cell types.
Macrophage Colony-Stimulating Factor (M-CSF)
Drives differentiation, proliferation, and survival of monocytes and macrophages.
Nerve Growth Factor (NGF)
Essential for neuronal survival, neurite outgrowth, and differentiation of sensory and sympathetic neurons.
Oncostatin M (OSM)
Regulates cell differentiation, inflammation, tissue remodeling, and regenerative processes.
Platelet-Derived Growth Factor (PDGF)
Stimulates cell proliferation, migration, angiogenesis, and tissue repair.
Stem Cell Factor (SCF)
Maintains hematopoietic stem cells and supports stem cell survival through c-Kit signaling.
Thrombopoietin (TPO)
Promotes megakaryocyte development, platelet production, and hematopoietic stem cell maintenance.
Vascular Endothelial Growth Factor (VEGF)
Stimulates angiogenesis, endothelial cell proliferation, and vascular development.